Innovating Biomaterials and Biointerface Design

At the Min Lab, we aim to develop and implement general methodologies to study complex material-biology interactions in both 3D space and time, in diverse contexts, laying the scientific foundation for transformative advances in disease diagnosis, treatment, and prevention. Our research encompasses a broad range of biomedical topics, such as cancer, sepsis, traumatic brain injury, tissue damage/repair, pathogenic infections, and immune engineering.

Current lab research thrusts include:

    • Understanding and Harnessing Material-Biology Interactions
    • Toward Controlled Drug Delivery
    • Advanced Molecular Profiling for Disease Diagnosis


We seek to fill critical gaps in understanding and utilizing material-biology interactions, particularly the impact of surface topography on biological responses. We recently developed an innovative and versatile bottom-up nanofabrication approach that enables the creation of controlled nano/micro-topographies on various substrates at large scales. This method features dynamic topography, allowing for reversible shape transformations without morphological distortion.


Another research area of focus has been the development of advanced molecular and cellular profiling methods for understanding disease progression and therapy. My group is actively engaged in three biosensing projects: (i) Pediatric Glioma EV Profiling; (ii) Microfluidic Sensor for Brain Injury Diagnosis.